![]() ![]() We take a step towards addressing this challenge, by using COSMOS, a cloud-enabled workflow management system, to develop GenomeKey, an NGS whole genome analysis workflow. The clinical potential of NGS will not be realized until robust and routine whole genome sequencing data can be accurately rendered to medically actionable reports within a time window of hours and at scales of economy in the 10's of dollars. While next-generation sequencing ( NGS) costs have plummeted in recent years, cost and complexity of computation remain substantial barriers to the use of NGS in routine clinical care. Souilmi, Yassine Lancaster, Alex K Jung, Jae-Yoon Rizzo, Ettore Hawkins, Jared B Powles, Ryan Amzazi, Saaïd Ghazal, Hassan Tonellato, Peter J Wall, Dennis P Scalable and cost-effective NGS genotyping in the cloud. ![]()
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